EF手形域 | 人类基因组 | 生物系统数据库

词条	EF手形域
	ID: 70064 添加时间: 2024/7/23 0:16:56 修改时间: 2025/3/11 1:26:06 词条编辑: 刘小见
同义词	EF-hand domain containing
层次树
外库	HGNC组
父-分类	域和家族
子-分类	CREC家族(5) CREC family ★FKBP脯氨酰异构酶9/10(2) FKBP prolyl isomerase 9/10;FKBP9/10 ★NKD,WNT信号通路抑制物(2) NKD inhibitor of WNT signaling pathway N-末端EF手形钙结合蛋白(3) N-terminal EF-hand calcium binding proteins;NECAB ★RAB11家族作用蛋白3/4(2) RAB11 family interacting protein 3/4;RAB11FIP3/4 ★RALBP1关联Eps域(2) RALBP1 associated Eps domain;REPS ★RAS和EF手形域(3) Ras and EF-hand domain RAS鸟苷酸释放蛋白(4) RAS guanyl releasing proteins;RASGRP S100钙结合蛋白(20) S100 calcium binding proteins;S100 SPARC家族(5) SPARC family ★癌调蛋白(2) oncomodulin;OCM ★表皮生长因子受体通路底物15(2) epidermal growth factor receptor pathway substrate 15;EPS15 蛋白磷酸酶3调节亚基(2) Protein phosphatase 3 regulatory subunits;PPP3R ★蛋白磷酸酶含EF手形域(2) protein phosphatase with EF-hand domain;PPEF 辅肌动蛋白(2) Actinins;ACTN ★钙调蛋白(7) calmodulin family ★钙结合蛋白1/2/4/5(4) calcium binding protein 1/2/4/5 ★钙结合蛋白7/8(2) calcium binding protein 7/8 ★钙磷蛋白(3) calcyphosine;CAPS ★核结合蛋白?(2) nucleobindin;NUCB 肌球蛋白轻链,1类(4) Myosin light chains, class 1 肌球蛋白轻链,2类(7) Myosin light chains, class 2 ★钾电压门控通道作用蛋白(4) potassium voltage-gated channel interacting protein ★交叉蛋白?(2) intersectin ★磷脂酶Cη(2) phospholipase C eta;PLCH ★鸟苷酸环化酶激活物1(3) guanylate cyclase activator 1;GUCA1 ★溶血磷脂酰胆碱酰基转移酶1/2(2) lysophosphatidylcholine acyltransferase 1/2;LPCAT1/2 ★溶质载体家族25成员12/13(2) solute carrier family 25 member 12/13;SLC25A12/13 ★溶质载体家族25成员23/24/25(3) solute carrier family 25 member 23/24/25;SLC25A23/24/25 ★双氧化酶(2) dual oxidase;DUOX ★丝聚蛋白(2) filaggrin;FLG ★同种异体移植炎性因子1(2) allograft inflammatory factor 1 中心蛋白?(4) centrin ANKEF1 锚蛋白重复和EF-手形域1;ankyrin repeat and EF-hand domain containing 1 CACNA1B 钙电压门控通道亚基α1 B;calcium voltage-gated channel subunit alpha1 B CACNA1E 钙电压门控通道亚基α1 E;calcium voltage-gated channel subunit alpha1 E CALB1 钙结合蛋白1;calbindin 1 CALB2 钙结合蛋白2;calbindin 2 CAPN1 钙蛋白酶1;calpain 1 CAPN11 钙蛋白酶11;calpain 11 CAPN12 钙蛋白酶12;calpain 12 CAPN14 钙蛋白酶14;calpain 14 CAPN2 钙蛋白酶2;calpain 2 CAPN3 钙蛋白酶3;calpain 3 CAPN8 钙蛋白酶8;calpain 8 CAPN9 钙蛋白酶9;calpain 9 CAPNS1(1) 钙蛋白酶小亚基1;calpain small subunit 1 CAPNS2 钙蛋白酶小亚基2;calpain small subunit 2 CGREF1 细胞生长调节物含EF-手形域1;cell growth regulator with EF-hand domain 1 CHP1(3) 钙调神经磷酸酶样EF-手形蛋白1;calcineurin like EF-hand protein 1 CHP2 钙调神经磷酸酶样EF-手形蛋白2;calcineurin like EF-hand protein 2 CIB1 钙和整联蛋白结合1;calcium and integrin binding 1 CIB2 钙和整联蛋白结合家族成员2;calcium and integrin binding family member 2 CIB3 钙和整联蛋白结合家族成员3;calcium and integrin binding family member 3 CIB4 钙和整联蛋白结合家族成员4;calcium and integrin binding family member 4 CLXN 钙轴蛋白?;calaxin CRNN cornulin DGKA 二酰甘油激酶α;diacylglycerol kinase alpha DGKB 二酰甘油激酶β;diacylglycerol kinase beta DGKG 二酰甘油激酶γ;diacylglycerol kinase gamma DNAH7 动力蛋白轴丝重链7;dynein axonemal heavy chain 7 DST 肌张力障碍蛋白;dystonin DUOX2 双氧化酶2;dual oxidase 2 EFCAB10 EF-手形钙结合域10;EF-hand calcium binding domain 10 EFCAB11 EF-手形钙结合域11;EF-hand calcium binding domain 11 EFCAB12 EF-手形钙结合域12;EF-hand calcium binding domain 12 EFCAB13 EF-手形钙结合域13;EF-hand calcium binding domain 13 EFCAB14(1) EF-手形钙结合域14;EF-hand calcium binding domain 14 EFCAB2 EF-手形钙结合域2;EF-hand calcium binding domain 2 EFCAB3(1) EF-手形钙结合域3;EF-hand calcium binding domain 3 EFCAB5 EF-手形钙结合域5;EF-hand calcium binding domain 5 EFCAB6 EF-手形钙结合域6;EF-hand calcium binding domain 6 EFCAB7 EF-手形钙结合域7;EF-hand calcium binding domain 7 EFCAB8 EF-手形钙结合域8;EF-hand calcium binding domain 8 EFCAB9 EF-手形钙结合域9;EF-hand calcium binding domain 9 EFCC1 EF-手形和卷曲螺旋域1;EF-hand and coiled-coil domain containing 1 EFHB EF-手形域家族成员B;EF-hand domain family member B EFHC1 EF-手形域1;EF-hand domain containing 1 EFHC2 EF-手形域2;EF-hand domain containing 2 EFHD1 EF-手形域家族成员D1;EF-hand domain family member D1 EFHD2 EF-手形域家族成员D2;EF-hand domain family member D2 EHD1 EH域1;EH domain containing 1 EHD2 EH域2;EH domain containing 2 EHD3 EH域3;EH domain containing 3 EHD4 EH域4;EH domain containing 4 FKBP14 FKBP脯氨酰异构酶14;FKBP prolyl isomerase 14 FKBP7 FKBP脯氨酰异构酶7;FKBP prolyl isomerase 7 FSTL4 卵泡抑素样4;follistatin like 4 FSTL5 卵泡抑素样5;follistatin like 5 GCA 颗粒钙蛋白;grancalcin GNPTAB N-乙酰葡萄糖胺-1-磷酸转移酶亚基α和β;N-acetylglucosamine-1-phosphate transferase subunits alpha and beta GPD2 甘油-3-磷酸脱氢酶2;glycerol-3-phosphate dehydrogenase 2 HPCA 海马钙蛋白;hippocalcin HPCAL1 海马钙蛋白样1;hippocalcin like 1 HPCAL4 海马钙蛋白样4;hippocalcin like 4 HRNR hornerin LCP1 淋巴细胞细胞质基质蛋白1;lymphocyte cytosolic protein 1 LETM1(3) 亮氨酸拉链和EF-手形跨膜蛋白1;leucine zipper and EF-hand containing transmembrane protein 1 LETM2 亮氨酸拉链和EF-手形跨膜蛋白2;leucine zipper and EF-hand containing transmembrane protein 2 MACF1 微管肌动蛋白交联因子1;microtubule actin crosslinking factor 1 MCC MCC,WNT信号通路调节物;MCC regulator of WNT signaling pathway MCFD2(1) 多凝血因子缺乏症2,内质网货物受体复合物亚基;multiple coagulation factor deficiency 2, ER cargo receptor complex subunit MICU1 线粒体钙吸收1;mitochondrial calcium uptake 1 MICU2 线粒体钙吸收2;mitochondrial calcium uptake 2 MICU3 线粒体钙吸收家族成员3;mitochondrial calcium uptake family member 3 NCALD 神经钙蛋白δ;neurocalcin delta NCS1 神经元钙传感器1;neuronal calcium sensor 1 NIN ninein NINL ninein样;ninein like NOX5 NADPH氧化酶5;NADPH oxidase 5 PDCD6(1) 程序性细胞死亡6;programmed cell death 6 PEF1 五EF手形域1;penta-EF-hand domain containing 1 PKD2 多囊蛋白2,瞬时受体电位阳离子通道;polycystin 2, transient receptor potential cation channel PLCD1 磷脂酶Cδ1;phospholipase C delta 1 PLCD4 磷脂酶Cδ4;phospholipase C delta 4 PLCG1 磷脂酶Cγ1;phospholipase C gamma 1 PLCZ1 磷脂酶Cζ1;phospholipase C zeta 1 PLS1(1) 丝束蛋白?1;plastin 1 PLS3 丝束蛋白?3;plastin 3 PPP2R3A 蛋白磷酸酶2调节亚基B'α;protein phosphatase 2 regulatory subunit B'alpha PPP2R3B 蛋白磷酸酶2调节亚基B'β;protein phosphatase 2 regulatory subunit B'beta PRKCSH PRKCSH葡萄糖苷酶β亚基Ⅱ;PRKCSH beta subunit of glucosidase II PVALB 小清蛋白;parvalbumin RCVRN 恢复蛋白;recoverin RHBDL3 菱形样3;rhomboid like 3 RHOT1(3) ras同源物家族成员T1;ras homolog family member T1 RHOT2 ras同源物家族成员T2;ras homolog family member T2 RPTN repetin RYR2 兰尼碱受体2;ryanodine receptor 2 RYR3 兰尼碱受体3;ryanodine receptor 3 SCGN 促分泌蛋白,EF-手形钙结合蛋白;secretagogin, EF-hand calcium binding protein SELENON 硒蛋白N;selenoprotein N SPATA21 精子发生关联21;spermatogenesis associated 21 SPTA1 血影蛋白α,红细胞1;spectrin alpha, erythrocytic 1 SPTAN1 血影蛋白α,非红细胞1;spectrin alpha, non-erythrocytic 1 SRI(3) sorcin SWAP70 转换?B细胞复合体亚基SWAP70;switching B cell complex subunit SWAP70 TBC1D8B TBC1域家族成员8B;TBC1 domain family member 8B TBC1D9 TBC1域家族成员9;TBC1 domain family member 9 TBC1D9B TBC1域家族成员9B;TBC1 domain family member 9B TCHH 毛透明蛋白;trichohyalin TESC tescalcin TNNC1 肌钙蛋白C1,慢速骨骼肌和心肌型;troponin C1, slow skeletal and cardiac type TNNC2 肌钙蛋白C2,快速骨骼肌型;troponin C2, fast skeletal type USP32(4) 泛素特异性肽酶32;ubiquitin specific peptidase 32 VSNL1 视锥蛋白样1;visinin like 1 ZZEF1 锌指ZZ型和EF手形域1;zinc finger ZZ-type and EF-hand domain containing 1 S100A7L2 S100钙结合蛋白A7样2;S100 calcium binding protein A7 like 2
假基因	EFCAB15P EF-手形钙结合域15,假基因;EF-hand calcium binding domain 15, pseudogene
简介	The EF hand is a helix-loop-helix structural domain or motif found in a large family of calcium-binding proteins. The EF-hand motif contains a helix-loop-helix topology, much like the spread thumb and forefinger of the human hand, in which the Ca 2+ ions are coordinated by ligands within the loop. The motif takes its name from traditional nomenclature used in describing the protein parvalbumin, which contains three such motifs and is probably involved in muscle relaxation via its calcium-binding activity. The EF-hand consists of two alpha helices linked by a short loop region (usually about 12 amino acids ) that usually binds calcium ions.