生物系统数据库
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词条

XYLB

ID: 68082 添加时间: 2024/7/4 12:25:27 修改时间: 2024/12/31 19:06:17 词条编辑: 刘小见
同义词木酮糖激酶 ; xylulokinase;FLJ10343 ; FLJ12539 ; D-xylulokinase ; xylulose kinase ;
曾用名xylulokinase homolog (H. influenzae) ; 
基因信息染色体位置: 3p22.2   基因类型: 蛋白编码基因 , 酶
层次树 人类基因组 2.转移酶 2.7-转移酶.含磷基团 2.7.1-激酶.羟基受体
外库HGNC   GeneCards   NCBI   Kegg   KO   UniProt   Signor   Ensembl   AllianceGenome   UCSC   VEGA   OMIM   PubMed1 2   RefSeq   ENA   CCDS1 ,2
父-分类
酶功能
简介
The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. [provided by RefSeq, Aug 2009]
Diseases associated with XYLB include Pentosuria and Sigmoid Disease. Among its related pathways are Glycosaminoglycan metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include phosphotransferase activity, alcohol group as acceptor and D-xylulokinase activity. An important paralog of this gene is GK2.
Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.
xylulokinase-like,homolog to xylulokinase of H influenzae