| 简介 | Predicted to enable tRNA 2'-phosphotransferase activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to act upstream of or within regulation of protein kinase activity. [provided by Alliance of Genome Resources, Nov 2024]
Diseases associated with TRPT1 include Pontocerebellar Hypoplasia. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and tRNA 2'-phosphotransferase activity.
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
mitochondrion 3 |
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