| 简介 | ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008]
Diseases associated with ADPGK include Opitz-Kaveggia Syndrome. Among its related pathways are Glycolysis (REACTOME) and Glycosaminoglycan metabolism. Gene Ontology (GO) annotations related to this gene include kinase activity and ADP-specific glucokinase activity.
Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor.
GDP and CDP can replace ADP, but with reduced efficiency (By similarity).
Secreted {ECO:0000305}4 |
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